A) UNICOAT MEC (Solvent base)
B) UNICOAT MECA (Water base)
» This group of polymers are widely used in the global market for enteric coating applications as they contain free carboxylic acid groups that are ionized whenever the pH of the environment exceeds 5.5.
» Metha acrylic acid methyl methacrylate copolymers (UNICOAT Li00 AND Li0055), and metha acrylic acid ethyl acrylate copolymer (UNICOAT L30D) are the preferred choice of coating polymers for enteric formulations. They allow targeting of specific areas of the intestine.
UNICOAl MEC Reconstitution Level 10.0% Avg. Weight Gain 7 – 8%
UNICOAl MEC A Reconstitution Level 25.0% Avg. Weight Gain 7 – 8%
| Conventional Coater | Auto Coater | Conventional Coater | Auto Coater | Auto Coater | |
| COATING EQUIPMENT | 12″ PAN | 24″ PAN | 36″ PAN | 48″ PAN | 60″ PAN |
| PAN Speed (rpm) | 18- 20 | 10-14 | 8-12 | 3-5 | 1.5-3 |
| Tablet Charge ( Kg ) | 0.5 – 1 | 10-15 | 40-50 | 100-130 | 250-300 |
| Tablet Bed Tempreature(°C) | 30-33 | 30-33 | 30-33 | 30-33 | 30-33 |
| Spray Rate (g/min) | 8.0-12.0 | 25-35 | 60-75 | 200-250 | 350-400 |
| Inlet Air Tempreature(°C) | 40-45 | 40-45 | 40-45 | 40-45 | 40-45 |
| Weight gain (%) on Tablet | 7-8 | 7-8 | 7-8 | 7-8 | 7-8 |
